Obesity-induced dysregulation of skin-resident PPARγ+ Treg cells promotes IL-17A-mediated psoriatic inflammation
Pulavendran Sivasami, Cody Elkins, Pamela P. Diaz-Saldana, Kyndal Goss, Amy Peng, Michael Hamersky, Jennifer Bae, Miaoer Xu, Brian P. Pollack, Edwin M. Horwitz, Christopher D. Scharer, Lindsey Seldin, Chaoran Li
Topics & Concepts
InflammationFOXP3PsoriasisImmunologyBiologyPeroxisome proliferator-activated receptorLipotoxicityRegulatory T cellInterleukin 17ReceptorCancer researchEndocrinologyMedicineInternal medicineT cellImmune systemObesityIL-2 receptorInsulin resistanceImmune Cell Function and InteractionT-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways