C- to N-Center Remote Heteroaryl Migration via Electrochemical Initiation of N Radical by Organic Catalyst
Chengkou Liu, Qiang Jiang, Yang Lin, Zheng Fang, Kai Guo
Abstract
Herein an exogenous oxidant- and metal-free electrochemical heteroaryl migration triggered by N radicals to construct new N-C bonds was developed. This methodology features a high atom economy and utilization rate of energy, and it is insensitive to water and air. Moreover, a user-friendly undivided cell was employed. The use of an organic catalyst makes it more efficient, green, and practical.
Topics & Concepts
ChemistryCatalysisElectrochemistryCenter (category theory)Combinatorial chemistryPhotochemistryOrganic chemistryCrystallographyElectrodePhysical chemistryRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods