Exploration of thiazine Schiff bases as promising urease inhibitors: Design, synthesis, enzyme inhibition, kinetic analysis, ADME/T evaluation, and molecular docking studies
Yousaf Khan, Mehwish Solangi, Khalid Mohammed Khan, Nisar Ullah, Jamshed Iqbal, Zahid Hussain, Imtiaz Khan, Uzma Salar, Muhammad Taha
Topics & Concepts
ADMEChemistryEnzyme inhibitionThiazineEnzymeDocking (animal)UreaseBiochemistryStereochemistryCombinatorial chemistryOrganic chemistryIn vitroMedicineNursingMicrobial Applications in Construction MaterialsSynthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activity