Litcius/Paper detail

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

Jordan L. Doman, Aditya Raguram, Gregory A. Newby, David R. Liu

2020Nature Biotechnology453 citationsDOIOpen Access PDF

Topics & Concepts

CytosineDNACas9Genome editingBase (topology)CRISPRComputational biologyComputer scienceGeneticsBiologyMathematicsGeneMathematical analysisCRISPR and Genetic EngineeringRNA regulation and diseaseCytomegalovirus and herpesvirus research