Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
Xiaoling Zhang, Weihong Du, Shuxia Qian, Xudong Lü, Xin Yu, Hai-lun Fang, Jiali Dong, Min Kyung Song, Yanyun Sun, Xiaoqiang Wu, Yufei Shen, Yanan Hao, Min-hui Shen, Beiqun Zhou, Yanping Wang, Congying Xu, Xinchun Jin
Topics & Concepts
OccludinDownregulation and upregulationBlood–brain barrierEvans BlueProinflammatory cytokineMicrogliaNeuroprotectionParacellular transportMedicineCell biologyPharmacologyChemistryTight junctionCancer researchImmunologyInflammationBiologyEndocrinologyBiochemistryGeneCentral nervous systemPermeability (electromagnetism)MembraneBarrier Structure and Function StudiesCancer-related molecular mechanisms researchCaveolin-1 and cellular processes