Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis
Jia-Wang Liu, Jiayan Lu, Chen Zhang, Qingyang Zhou, Cooper S. Jamieson, Changhui Shang, K. N. Houk, Jiahai Zhou, Youcai Hu
Topics & Concepts
ChemistryCycloadditionGlycanEnzymeTandemBiosynthesisBiocatalysisCatalysisStereochemistryIntermolecular forceEnzyme catalysisCombinatorial chemistryBiochemistryGlycoproteinOrganic chemistryReaction mechanismMoleculeComposite materialMaterials sciencePlant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisGlycosylation and Glycoproteins Research