Prolonged sevoflurane exposure causes abnormal synapse development and dysregulates beta-neurexin and neuroligins in the hippocampus in neonatal rats
Wenhua Zhang, Yanxin Chen, Jingwen Qin, Junming Lu, Y. Fan, Ziwen Shi, Xingrong Song, Chuanxiang Li, Tianyun Zhao
Topics & Concepts
SevofluraneHippocampusExcitatory postsynaptic potentialPostsynaptic densityHippocampal formationGephyrinNeurexinSynaptogenesisGABAA receptorPostsynaptic potentialInhibitory postsynaptic potentialInternal medicineNeuroscienceNeuroliginEndocrinologyAnesthesiaMedicineChemistryBiologyReceptorGlycine receptorBiochemistryGlycineAmino acidAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive DisordersNeonatal and fetal brain pathology