IRE1α-targeting downregulates ABC transporters and overcomes drug resistance of colon cancer cells
Qiang Gao, Xiuxiu Li, Yiming Xu, Jinzhao Zhang, Shi-di Rong, Yan-qing Qin, Jing Fang
Topics & Concepts
ATP-binding cassette transporterAbcg2Drug resistanceXBP1ABCC1Colorectal cancerPharmacologyDrugCancer researchBiologyCancerIn vivoCancer cellTransporterBiochemistryGeneticsGeneRNA splicingRNADrug Transport and Resistance MechanismsEndoplasmic Reticulum Stress and DiseaseLiver Disease Diagnosis and Treatment