Novel HIV-1 capsid-targeting small molecules of the PF74 binding site
Lei Wang, Mary C. Casey, Sanjeev Kumar V. Vernekar, Rajkumar Lalji Sahani, Jayakanth Kankanala, Karen A. Kirby, Haijuan Du, Atsuko Hachiya, Huanchun Zhang, Philip R. Tedbury, Jiashu Xie, Stefan G. Sarafianos, Zhengqiang Wang
Topics & Concepts
ChemistryMoietyChemotypeIndole testStereochemistrySmall moleculeCapsidMetabolic stabilityBinding siteCombinatorial chemistryBiochemistryIn vitroGeneEssential oilChromatographyHIV Research and TreatmentHIV/AIDS drug development and treatmentHepatitis C virus research