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Functional coculture of sympathetic neurons and cardiomyocytes derived from human-induced pluripotent stem cells

Annika Winbo, Suganeya Ramanan, Emily Eugster, Stefan Jovinge, Jonathan R. Skinner, Johanna M. Montgomery

2020American Journal of Physiology-Heart and Circulatory Physiology55 citationsDOI

Abstract

We present data on a functional coculture between human-induced pluripotent stem cell-derived sympathetic neurons and cardiomyocytes. Moreover, this study adds significantly to the available data on the electrophysiological function of human-induced pluripotent stem cell-derived sympathetic neurons.

Topics & Concepts

Induced pluripotent stem cellStem cellHuman Induced Pluripotent Stem CellsNeuroscienceCell biologyFunction (biology)BiologyEmbryonic stem cellBiochemistryGeneNeuroscience and Neural EngineeringCardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research
Functional coculture of sympathetic neurons and cardiomyocytes derived from human-induced pluripotent stem cells | Litcius