Lumpy skin disease outbreaks in vietnam, 2020
Ha Thi Thanh Tran, Anh Duc Truong, Anh Kieu Dang, Duc Viet Ly, Chinh Nguyen, Nhu Thi Chu, Tuan Van Hoang, Huyen Thi Nguyen, Vinh T. Nguyen, Hoang Vu Dang
Abstract
Lumpy skin disease (LSD) is a transboundary, systemic, viral disease of cattle. The first outbreaks of LSD were reported in Lang Son Province of Vietnam (bordered to China), and an official document has been submitted to OIE on 1 November 2020. Here, we described first the genetic profiles of this pathogen based on four well-known marker regions. The LSD virus isolated in these first outbreaks was 100% identical to viruses isolated in China (2019) based on the p32 and RP030 genes. Additionally, it is very close to the virus isolated in Russia (2017) based on the p32, RP030, thymidine kinase and ORF103 genes (100%, 99.01%, 99.08% and 99.47% identities). This finding is new, and a success in LSD virus isolation using MDBK cells from first outbreaks is important for vaccine development to control and eradicate LSD in Vietnam.