Deubiquitinase OTUB1 regulates doxorubicin-induced cardiotoxicity via deubiquitinating c-MYC
Fei Xu, Tongtong Zang, Han Chen, Changyi Zhou, Rui Wang, Yue Yu, Li Shen, Juying Qian, Junbo Ge
Topics & Concepts
Terminal deoxynucleotidyl transferaseTUNEL assayOxidative stressBiologyMolecular biologyDoxorubicinApoptosisCardiotoxicityBlotCancer researchPharmacologyChemistryBiochemistryChemotherapyGeneGeneticsChemotherapy-induced cardiotoxicity and mitigationUbiquitin and proteasome pathwaysCell death mechanisms and regulation