Exposure to hydroxyapatite nanoparticles enhances Toll-like receptor 4 signal transduction and overcomes endotoxin tolerance in vitro and in vivo
Yuchen Hua, Jinjie Wu, Hongfeng Wu, Cheng Su, Xiangfeng Li, Qiang Ao, Qin Zeng, Xiangdong Zhu, Xingdong Zhang
Topics & Concepts
TLR4Innate immune systemSignal transductionLipopolysaccharideMacrophageImmune systemCell biologyToll-like receptorCytokineBiologyMaterials scienceMolecular biologyImmunologyIn vitroBiochemistryImmune Response and InflammationBone Metabolism and DiseasesImmune cells in cancer