Litcius/Paper detail

R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response

Magdalena P. Crossley, Chenlin Song, M Bocek, Jun‐Hyuk Choi, Joseph N. Kousouros, Ataya Sathirachinda, Cindy Lin, Joshua R. Brickner, Gongshi Bai, Hannes Lans, Wim Vermeulen, Monther Abu-Remaileh, Karlene A. Cimprich

2022Nature300 citationsDOIOpen Access PDF

Topics & Concepts

BiologyInnate immune systemRNA Helicase ARNACell biologyDNAMolecular biologyGeneticsHelicaseGeneImmune systemCRISPR and Genetic EngineeringDNA Repair MechanismsImmune Cell Function and Interaction