Optimization of sample extraction and injection-related parameters in HILIC performance for polar metabolite analysis. Application to the study of a model of pulmonary hypertension
María Morán-Garrido, Patricia Muñoz-Escudero, Ana García‐Álvarez, Inés García‐Lunar, Coral Barbas, Jorge Sáiz
Topics & Concepts
ChemistryHydrophilic interaction chromatographyChromatographyAnalyteAcetonitrileSolventMetaboliteExtraction (chemistry)Sample preparationPolarMethanolHigh-performance liquid chromatographyBiochemistryOrganic chemistryAstronomyPhysicsAnalytical Chemistry and ChromatographyMetabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications