Acid-catalyzed proton exchange as a novel approach for relaxivity enhancement in Gd-HPDO3A-like complexes
Loredana Leone, Mariangela Boccalon, Giuseppe Ferrauto, István Fábián, Zsolt Baranyai, Lorenzo Tei
Abstract
-complexes. Thus, proton exchange provides an important opportunity to enhance the relaxivity of contrast agents, providing that labile protons close to the paramagnetic center can contribute.
Topics & Concepts
AmideProtonChemistryCatalysisSide chainCombinatorial chemistryOrganic chemistryPolymerPhysicsQuantum mechanicsLanthanide and Transition Metal ComplexesMetal-Organic Frameworks: Synthesis and ApplicationsRadioactive element chemistry and processing