Introduction of a β-leucine residue instead of leucine9 and glycine10 residues in Temporin L for improved cell selectivity, stability and activity against planktonic and biofilm of methicillin resistant S. aureus
Neeraj Kumar Verma, Rikeshwer Prasad Dewangan, Munesh Kumar Harioudh, Jimut Kanti Ghosh
Topics & Concepts
ChemistryVesicleAntimicrobialPeptideBiofilmMembraneAntimicrobial peptidesBiochemistryLipid bilayerProteaseLeucineCytotoxicityAntibacterial activityBacteriaBiophysicsAmino acidIn vitroBiologyEnzymeOrganic chemistryGeneticsAntimicrobial Peptides and ActivitiesLipid Membrane Structure and BehaviorBiochemical and Structural Characterization