Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice
Mohammad Rehan, Deepali Kurundkar, Ashish Kurundkar, Naomi J. Logsdon, S. Ray Smith, Diptiman Chanda, Karen Bernard, Yan Y. Sanders, Jessy S. Deshane, K.G. Dsouza, Sunad Rangarajan, Jaroslaw W. Zmijewski, Victor J. Thannickal
Topics & Concepts
SIRT3SirtuinFibrosisApoptosisLungCancer researchDownregulation and upregulationPulmonary fibrosisIdiopathic pulmonary fibrosisTranscription factorBiologyMedicineMyofibroblastImmunologyPathologyInternal medicineGeneGeneticsAcetylationFOXO transcription factor regulationSirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy