Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome
Wei Yuan, Teng Liu, Yuanyi Wang, Shuang He, Feng Zhang, Xiao-bian Wang, Shihua Deng, Ting Zhang, Dong-ming Wu, Ying Xu
Topics & Concepts
InflammasomePyroptosisAutophagyGoutInflammationPyrin domainLysosomeMedicineArthritisChemistryCell biologyApoptosisImmunologyBiologyInternal medicineBiochemistryEnzymeInflammasome and immune disordersGout, Hyperuricemia, Uric AcidStreptococcal Infections and Treatments