Interactions of nanoparticles with living and synthetic bio-membranes
Rashad Kariuki, Kalpani A. Mirihana, Rowan Penman, Andrew Hung, Nastaran Meftahi, Gary Bryant, Paul A. Ramsland, Kislon Voı̈tchovsky, Charlotte E. Conn, Claudia Contini, Saffron J. Bryant, Andrew J. Christofferson, Aaron Elbourne
Abstract
experimental and theoretical techniques, to isolate the underpinning interaction mechanisms of NPs at the bio-interface. This review aims to unify the current literature regarding the biophysical interactions between inorganic and organic NPs and bio-membrane interfaces, including living and synthetic systems. The article will explore the role of membrane composition, NP morphology and chemistry, and the forces involved in interactions between the two entities. Identifying the fundamental influences of NP-membrane interactions, primarily synthetic NPs as these are more clinically applied, will allow for the more effective design of novel biomedical agents for future therapies.