Oxocrebanine: A Novel Dual Topoisomerase inhibitor, Suppressed the Proliferation of Breast Cancer Cells MCF-7 by Inducing DNA Damage and Mitotic Arrest
Lei Yu, Shuang Han, Lang Lang, Hui Song, Caiyun Zhang, Lin Dong, Shaohua Jia, Ying Zhang, Di Xiao, Jun Liu, Ying Xu, Xiaopo Zhang
Topics & Concepts
MCF-7Acridine orangeCancer cellMTT assayMitosisTopoisomeraseMolecular biologyCell growthBiologyCell cycleChemistryCellApoptosisCell biologyBiochemistryDNACancerHuman breastGeneticsCancer therapeutics and mechanismsTraditional and Medicinal Uses of AnnonaceaeBioactive natural compounds