Litcius/Paper detail

Erratum to: Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2

Toni Luise Meister, Yannick Brüggemann, Daniel Tödt, Carina Conzelmann, Janis A. Müller, Rüdiger Groß, Jan Münch, Adalbert Krawczyk, Jörg Steinmann, Jochen Steinmann, Stephanie Pfaender, Eike Steinmann

2020The Journal of Infectious Diseases104 citationsDOIOpen Access PDF

Abstract

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early coronavirus disease 2019, thus advocating application of oral antiseptics. However, the antiviral efficacy of oral rinsing solutions against SARS-CoV-2 has not been examined. Here, we evaluated the virucidal activity of different available oral rinses against SARS-CoV-2 under conditions mimicking nasopharyngeal secretions. Several formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-CoV-2.

Topics & Concepts

SalivaMedicineCoronavirusTransmission (telecommunications)Coronavirus disease 2019 (COVID-19)ThroatSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicRespiratory systemVirusViral loadImmunologyVirologyDiseaseInternal medicineInfectious disease (medical specialty)SurgeryEngineeringElectrical engineeringDental Research and COVID-19SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing