A pH-sensitive DNA tetrahedron for targeted release of anthracyclines: Binding properties investigation and cytotoxicity evaluation
Tianxin Weng, Lu Wang, Xinpeng Zhang, Yushu Wu, Yanna Zhao, Yongfang Zhang, Jun Han, Min Liu
Topics & Concepts
CytotoxicityDoxorubicinChemistryNanocarriersDNABiophysicsBinding constantReceptor–ligand kineticsIn vitroAptamerFootprintingCombinatorial chemistryBinding siteBiochemistryStereochemistryDrug deliveryMolecular biologyOrganic chemistryBiologyBase sequenceReceptorGeneticsChemotherapyAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery