Doxorubicin covalently conjugated heparin displays anti-cancer activity as a self-assembled nanoparticle with a low-anticoagulant effect
Jae-Hyeon Lee, Seong-Bin Yang, Jun Hyuck Lee, Hansol Lim, Seokwoo Lee, Tae‐Bong Kang, Ji-Hong Lim, Young Jun Kim, Jooho Park
Topics & Concepts
DoxorubicinConjugated systemHeparinCovalent bondAnticoagulantChemistryNanoparticlePharmacologyNanotechnologyPolymerMaterials scienceMedicineBiochemistryChemotherapyOrganic chemistryInternal medicineProteoglycans and glycosaminoglycans researchDendrimers and Hyperbranched PolymersNanoparticle-Based Drug Delivery