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Novel xanthine oxidase inhibitory peptides derived from whey protein: identification, in vitro inhibition mechanism and in vivo activity validation

Xiaofen Qi, Hao Chen, Kaifang Guan, Yue Sun, Rongchun Wang, Qiming Li, Ying Ma

2022Bioorganic Chemistry49 citationsDOI

Topics & Concepts

ChemistryIn vivoXanthine oxidaseHydrolysateHyperuricemiaCircular dichroismBiochemistryDocking (animal)IC50In vitroPharmacologyUric acidEnzymeHydrolysisBiologyNursingMedicineBiotechnologyGout, Hyperuricemia, Uric AcidPharmacological Effects of Natural CompoundsAlcohol Consumption and Health Effects
Novel xanthine oxidase inhibitory peptides derived from whey protein: identification, in vitro inhibition mechanism and in vivo activity validation | Litcius