Seratrodast, a thromboxane A2 receptor antagonist, inhibits neuronal ferroptosis by promoting GPX4 expression and suppressing JNK phosphorylation
Ying Hao, Yitao Ou, Cheng Zhang, Hao Chen, Yue Hu, Zhongjin Yang, Xiaofen Zhong, Wenhui Hu, Ping Sun
Topics & Concepts
PharmacologyGPX4PhosphorylationAntagonistDrugReceptor antagonistNeuroprotectionChemistryGlutathioneReceptorGlutathione peroxidaseMedicineBiochemistryEnzymeFerroptosis and cancer prognosisCholesterol and Lipid MetabolismRNA Research and Splicing