Liver Function Derangement in Patients with Severe Fever and Thrombocytopenia Syndrome
Sihong Lu, Ling Xu, Boyun Liang, Hua Wang, Tong Wang, Tiandan Xiang, Sumeng Li, Lei Fan, Junyuan Li, Cheng Peng, Xin Zheng
Abstract
Background and Aims: Patients with severe fever with thrombocytopenia syndrome (SFTS) commonly show liver function impairment. This study aimed to characterize the liver function indices in SFTS patients and investigate their association with mortality. Methods: . Results: experiment, SFTSV infected and replicated inside Huh7 cells. Conclusions: Liver injury is common in SFTS patients. ALT and ALP were independent predictors of SFTS-related mortality. Frequent monitoring and evaluation of liver function indices are needed for SFTS patients.
Topics & Concepts
MedicineDerangementPediatricsIntensive care medicineMathematicsCombinatoricsViral Infections and VectorsViral Infections and Outbreaks ResearchMosquito-borne diseases and control