Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells
Celestine N. Wanjalla, Wyatt J. McDonnell, Ramesh Ram, Abha Chopra, Rama Gangula, Shay Leary, Mona Mashayekhi, Joshua D. Simmons, Christian M. Warren, Samuel Bailin, Curtis L. Gabriel, Liang Guo, Briana D. Furch, Morgan C. Lima, Beverly Woodward, LaToya Hannah, Mark A. Pilkinton, Daniela T. Fuller, Kenji Kawai, Renu Virmani, Aloke V. Finn, Alyssa H. Hasty, S. Mallal, Spyros A. Kalams, John R. Koethe
Abstract
T cells in adipose tissue of persons with HIV.
Topics & Concepts
Adipose tissueCytotoxic T cellBiologyAdipocyteAdipose tissue macrophagesDiabetes mellitusEndocrinologyImmunologyInternal medicineMedicineWhite adipose tissueBiochemistryIn vitroHIV-related health complications and treatmentsDiabetes and associated disordersAdipokines, Inflammation, and Metabolic Diseases