Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2
Wan‐Chen Tsai, Nathaniel C. Gilbert, Amanda Ohler, Michelle Armstrong, Steve Perry, Chakrapani Kalyanaraman, Adam Yasgar, Ganesha Rai, Anton Simeonov, Ajit Jadhav, Melissa Standley, Hsiau‐Wei Lee, Phillip Crews, Anthony T. Iavarone, Matthew P. Jacobson, David B. Neau, Adam R. Offenbacher, Marcia E. Newcomer, Theodore R. Holman
Topics & Concepts
ChemistryMoietyStereochemistryDocking (animal)ImidazoleHydrogen–deuterium exchangeSmall moleculeMolecular modelEnzymeBiochemistryOrganic chemistryHydrogenMedicineNursingSynthesis and Biological EvaluationBioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stress