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Photoredox catalytic phosphine-mediated deoxygenative alkynylation of carboxylic acids with alkynyl sulfones for alkynone synthesis

Wen-Huan Tang, Li‐Yuan Wu, Quan‐Quan Zhou, Jie‐Ping Wan

2025Organic Chemistry Frontiers13 citationsDOI

Abstract

The synthesis of ynones has been realized via visible light-induced alkynylation of carboxylic acids with alkynyl sulfones as the alkynyl source, providing a mild and green new protocol for the synthesis of useful ynones.

Topics & Concepts

ChemistryAlkynylationPhosphineCatalysisCombinatorial chemistryOrganic chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsRadical Photochemical Reactions
Photoredox catalytic phosphine-mediated deoxygenative alkynylation of carboxylic acids with alkynyl sulfones for alkynone synthesis | Litcius