Green Asymmetric Organocatalysis
Dominika Krištofíková, Viktória Modrocká, Mária Mečiarová, Radovan Šebesta
Abstract
Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral compounds that are needed as medicines, crop protection agents, and other bioactive molecules. It can be effectively combined with various green chemistry methodologies. Intensification techniques, such as ball milling, flow, high pressure, or light, bring not only higher yields, faster reactions, and easier product isolation, but also new reactivities. More sustainable reaction media, such as ionic liquids, deep eutectic solvents, green solvent alternatives, and water, also considerably enhance the sustainability profile of many organocatalytic reactions.
Topics & Concepts
OrganocatalysisGreen chemistryChemistryIonic liquidEnantioselective synthesisOrganic chemistrySolventCatalysisCombinatorial chemistryNanotechnologyMaterials scienceAsymmetric Synthesis and CatalysisIonic liquids properties and applicationsInnovative Microfluidic and Catalytic Techniques Innovation