Litcius/Paper detail

The Congestion “Pandemic” in Acute Heart Failure Patients

Daniela Mocan, Radu Ioan Lala, Maria Pușchiță, Luminița Pilat, Dan Dărăbanțiu, Adina Pop‐Moldovan

2024Biomedicines11 citationsDOIOpen Access PDF

Abstract

Congestion not only represents a cardinal sign of heart failure (HF) but is also now recognized as the primary cause of hospital admissions, rehospitalization, and mortality among patients with acute heart failure (AHF). Congestion can manifest through various HF phenotypes in acute settings: volume overload, volume redistribution, or both. Recognizing the congestion phenotype is paramount, as it implies different therapeutic strategies for decongestion. Among patients with AHF, achieving complete decongestion is challenging, as more than half still experience residual congestion at discharge. Residual congestion is one of the strongest predictors of future cardiovascular events and poor outcomes. Through this review, we try to provide a better understanding of the congestion phenomenon among patients with AHF by highlighting insights into the pathophysiological mechanisms behind congestion and new diagnostic and management tools to achieve and maintain efficient decongestion.

Topics & Concepts

MedicineHeart failureVolume overloadPandemicIntensive care medicineInternal medicineCoronavirus disease 2019 (COVID-19)DiseaseInfectious disease (medical specialty)Heart Failure Treatment and ManagementMembrane-based Ion Separation TechniquesCardiovascular Function and Risk Factors
The Congestion “Pandemic” in Acute Heart Failure Patients | Litcius