Clinically used antifungal azoles as ligands for gold(<scp>iii</scp>) complexes: the influence of the Au(<scp>iii</scp>) ion on the antimicrobial activity of the complex
Nevena Lj. Stevanović, Jakob Kljun, Ivana Aleksić, Sanja Škaro Bogojević, Dušan Milivojević, Aleksandar M. Veselinović, Iztok Turel, Miloš I. Djuran, Jasmina Nikodinović‐Runić, Biljana Đ. Glišić
Abstract
controlled by quorum sensing, and increased cell survival after exposure to this bacterium. These findings could be of importance for the development of novel gold(III)-based antivirulence therapeutic agents that attenuate virulence without pronounced effect on the growth of the pathogens, offering a lower risk for resistance development.
Topics & Concepts
EconazoleChemistryAzoleImidazoleAntimicrobialClotrimazoleErgosterolCombinatorial chemistryMiconazoleStereochemistryMicrobiologyBiochemistryAntifungalOrganic chemistryBiologyMetal complexes synthesis and propertiesNanocomposite Films for Food PackagingSynthesis and Biological Evaluation