Elucidating the Role of O<sub>2</sub> Uncoupling in the Oxidative Biodegradation of Organic Contaminants by Rieske Non-heme Iron Dioxygenases
Charlotte E. Bopp, Nora M. Bernet, Hans‐Peter E. Kohler, Thomas B. Hofstetter
Abstract
uncoupling by Rieske dioxygenases, our work provides a mechanistic link between contaminant biodegradation, the generation of reactive oxygen species, and possible adaptation strategies of microorganisms to the exposure of new contaminants.
Topics & Concepts
DioxygenaseHydroxylationChemistryBiodegradationSubstrate (aquarium)HemeEnzymeMetabolic pathwayCatalysisBiochemistryOrganic chemistryBiologyEcologyMetal-Catalyzed Oxygenation MechanismsMicrobial bioremediation and biosurfactantsHeme Oxygenase-1 and Carbon Monoxide