Rational designed highly sensitive NQO1-activated near-infrared fluorescent probe combined with NQO1 substrates in vivo: An innovative strategy for NQO1-overexpressing cancer theranostics
Qijie Gong, Fulai Yang, Jiabao Hu, Li Tian, Pengfei Wang, Xiang Li, Xiaojin Zhang
Topics & Concepts
ChemistryIn vivoFluorescenceNaphthoquinoneCancer cellCancerCancer researchBiophysicsBiochemistryMedicineBiotechnologyPhysicsQuantum mechanicsOrganic chemistryInternal medicineBiologyBioactive Compounds and Antitumor AgentsSynthesis and biological activityOrganic Chemistry Cycloaddition Reactions