Litcius/Paper detail

Phigaro: high-throughput prophage sequence annotation

Elizaveta V. Starikova, Polina Tikhonova, Nikita A. Prianichnikov, Chris M. Rands, Evgeny M. Zdobnov, Elena N. Ilina, Vadim M. Govorun

2020Bioinformatics235 citationsDOIOpen Access PDF

Abstract

SUMMARY: Phigaro is a standalone command-line application that is able to detect prophage regions taking raw genome and metagenome assemblies as an input. It also produces dynamic annotated 'prophage genome maps' and marks possible transposon insertion spots inside prophages. It is applicable for mining prophage regions from large metagenomic datasets. AVAILABILITY AND IMPLEMENTATION: Source code for Phigaro is freely available for download at https://github.com/bobeobibo/phigaro along with test data. The code is written in Python. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Topics & Concepts

ProphagePython (programming language)AnnotationComputer scienceSource codeGenomeMetagenomicsTransposable elementComputational biologyBiologyProgramming languageGeneticsArtificial intelligenceGeneBacteriophageEscherichia coliBacteriophages and microbial interactionsImmune cells in cancerCancer-related gene regulation