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An organometallic catalase mimic with exceptional activity, H<sub>2</sub>O<sub>2</sub> stability, and catalase/peroxidase selectivity

Zhuomin Lu, Ian V. Lightcap, Andrew G. Tennyson

2021Dalton Transactions11 citationsDOI

Abstract

reduction. Therapeutic effects of redox catalysts can be predicted with greater accuracy for catalysts that exhibit exclusively catalase activity, thereby facilitating the development of future redox therapeutic strategies for diseases.

Topics & Concepts

DisproportionationChemistryCatalaseABTSPeroxidaseRedoxCatalysisReactivity (psychology)Reactive oxygen speciesCombinatorial chemistryLigand (biochemistry)EnzymePhotochemistryAntioxidantBiochemistryOrganic chemistryReceptorDPPHMedicinePathologyAlternative medicineVanadium and Halogenation ChemistryMetal complexes synthesis and propertiesMetal-Catalyzed Oxygenation Mechanisms
An organometallic catalase mimic with exceptional activity, H<sub>2</sub>O<sub>2</sub> stability, and catalase/peroxidase selectivity | Litcius