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Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform

Thomas Gonatopoulos-Pournatzis, Michael Aregger, Kevin R. Brown, Shaghayegh Farhangmehr, Ulrich Braunschweig, Henry N. Ward, Kevin Ha, Alexander Weiß, Maximilian Billmann, Tanja Durbic, Chad L. Myers, Benjamin J. Blencowe, Jason Moffat

2020Nature Biotechnology153 citationsDOI

Topics & Concepts

Functional genomicsComputational biologyCRISPRExonCas9GenomicsGeneticsBiologyGenome editingGenomeGeneCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAnimal Genetics and Reproduction
Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform | Litcius