ZIF-8 with cationic defects toward efficient<sup>125</sup>I<sub>2</sub>uptake for<i>in vitro</i>radiotherapy of colon cancer
Xinxin Tian, Yitong Liu, Yan Li, Xinyu Qiu, Wen‐Hua Zhang, David James Young, Chen Qiu
Abstract
ZIF-8 with cationic defects shows enhanced I 2 uptake. One example was used to encapsulate in situ generated radioactive 125 I 2 for the in vitro radio-therapeutic treatment of colon cancer.
Topics & Concepts
Cationic polymerizationDenticityChemistryIodideCytotoxicityIn vitroLinkerLigand (biochemistry)Colorectal cancerCrystallographyNuclear chemistryCombinatorial chemistryRadiochemistryStereochemistryCancerInorganic chemistryBiochemistryPolymer chemistryMedicineCrystal structureComputer scienceOperating systemInternal medicineReceptorMetal-Organic Frameworks: Synthesis and ApplicationsChemical Synthesis and CharacterizationNanoplatforms for cancer theranostics