Emodin alleviates acute hypoxia-induced apoptosis in gibel carp (Carassius gibelio) by upregulating autophagy through modulation of the AMPK/mTOR pathway
Liyun Wu, Hongyan Li, Wenjie Xu, Bo Dong, Hancheng Geng, Junyan Jin, Dong Han, Haokun Liu, Xiaoming Zhu, Yunxia Yang, Shouqi Xie
Topics & Concepts
CarpBiologyHypoxia (environmental)AMPKAutophagyPI3K/AKT/mTOR pathwaySignal transductionOxidative stressDownregulation and upregulationEndocrinologyInternal medicineApoptosisCell biologyProtein kinase ABiochemistryKinaseGeneMedicineChemistryFisheryOxygenFish <Actinopterygii>Organic chemistryAutophagy in Disease and TherapyAdipose Tissue and MetabolismCancer, Hypoxia, and Metabolism