Effects of hydroxyl group in cyclo(Pro-Tyr)-like cyclic dipeptides on their anti-QS activity and self-assembly
Li Li, Zuxian Xu, Ruipin Cao, Jiaxin Li, Chang‐Jer Wu, Yinglu Wang, Hu Zhu
Abstract
-Tyr) formed assembly particles at the highest tested concentration. The findings revealed the structure-function relationship of this kind of cyclic dipeptides and provided basis for our follow-up research in the design and modification of anti-QS compounds.
Topics & Concepts
Quorum sensingChemistryStereochemistryBiofilmDipeptideHydroxyl radicalPseudomonas aeruginosaCyclic peptideAutoinducerPeptideCytotoxicityIn vitroBiochemistryRadicalBacteriaVirulenceGeneBiologyGeneticsBacterial biofilms and quorum sensingAntimicrobial Peptides and ActivitiesAntimicrobial Resistance in Staphylococcus