Litcius/Paper detail

Integrating personalized shape prediction, biomechanical modeling, and wearables for bone stress prediction in runners

Liangliang Xiang, Yaodong Gu, Kaili Deng, Zixiang Gao, Vickie Shim, Alan Wang, Justin Fernandez

2025npj Digital Medicine15 citationsDOIOpen Access PDF

Abstract

Running biomechanics studies the mechanical forces experienced during running to improve performance and prevent injuries. This study presents the development of a digital twin for predicting bone stress in runners. The digital twin leverages a domain adaptation-based Long Short-Term Memory (LSTM) algorithm, informed by wearable sensor data, to dynamically simulate the structural behavior of foot bones under running conditions. Data from fifty participants, categorized as rearfoot and non-rearfoot strikers, were used to create personalized 3D foot models and finite element simulations. Two nine-axis inertial sensors captured three-axis acceleration data during running. The LSTM neural network with domain adaptation proved optimal for predicting bone stress in key foot bones-specifically the metatarsals, calcaneus, and talus-during the mid-stance and push-off phases (RMSE < 8.35 MPa). This non-invasive, cost-effective approach represents a significant advancement for precision health, contributing to the understanding and prevention of running-related fracture injuries.

Topics & Concepts

Wearable computerStress (linguistics)Computer scienceStress fracturesPredictive modellingMedicineMachine learningPhysical therapyEmbedded systemLinguisticsPhilosophyLower Extremity Biomechanics and PathologiesSports Performance and TrainingOccupational Health and Performance
Integrating personalized shape prediction, biomechanical modeling, and wearables for bone stress prediction in runners | Litcius