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Hook loop dynamics engineering transcended the barrier of activity-stability trade-off and boosted the thermostability of enzymes

Wenya Chong, Zihan Zhang, Zhongyu Li, Shuaiqi Meng, Binbin Nian, Yi Hu

2024International Journal of Biological Macromolecules16 citationsDOI

Topics & Concepts

ThermostabilityEnzymeChemistryStability (learning theory)Molecular dynamicsLoop (graph theory)Biochemical engineeringProtein stabilityHookProtein engineeringBiochemistryComputer scienceEngineeringMathematicsComputational chemistryCombinatoricsMachine learningStructural engineeringEnzyme Catalysis and ImmobilizationMicrobial Metabolic Engineering and BioproductionProtein Structure and Dynamics
Hook loop dynamics engineering transcended the barrier of activity-stability trade-off and boosted the thermostability of enzymes | Litcius