The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes
Shawn M. Costello, Sophie R. Shoemaker, Helen T. Hobbs, Annalee W. Nguyen, Ching‐Lin Hsieh, Jennifer A. Maynard, Jason S. McLellan, John E. Pak, Susan Marqusee
Topics & Concepts
EctodomainTrimerChemistryEpitopeBiophysicsProtein structurePopulationCrystallographyEpitope mappingPeptide sequenceStereochemistryReceptorAntibodyBiochemistryBiologyDimerGeneticsSociologyGeneOrganic chemistryDemographySARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingBacillus and Francisella bacterial research