Recent advances on anticancer and antimicrobial activities of directly-fluorinated five-membered heterocycles and their benzo-fused systems
Ashraf A. Abbas, Thoraya A. Farghaly, Kamal M. Dawood
Abstract
their reduced cytotoxicity in non-cancerous cell lines. SAR study assigned that fluorinated heterocycles having various electron-donating or electron-withdrawing substituents significantly affected the anticancer and antimicrobial activities.
Topics & Concepts
AntimicrobialChemistryCombinatorial chemistryOrganic chemistryFluorine in Organic ChemistrySynthesis and Biological EvaluationSynthesis and Reactions of Organic Compounds