A copper-catalyzed four-component reaction of arylcyclopropanes, nitriles, carboxylic acids and <i>N</i>-fluorobenzenesulfonimide: facile synthesis of imide derivatives
Shengbiao Yang, Chunyang Liu, Xiaoyan Shangguan, Yan Li, Qian Zhang
Abstract
-fluorobenzenesulfonimide (NFSI) has been successfully developed, which represents the first example of a four-component reaction of non-donor-acceptor cyclopropanes. A wide range of imide derivatives were efficiently synthesized in excellent yields under mild conditions.
Topics & Concepts
ImideChemistryCopperCatalysisComponent (thermodynamics)Organic chemistryAcceptorCombinatorial chemistryPhysicsCondensed matter physicsThermodynamicsCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques