Late-Stage Functionalization of Living Organisms: Rethinking Selectivity in Biology
Andrew M. Giltrap, Yizhi Yuan, Benjamin G. Davis
Abstract
, mechanism and selectivity) we believe that the logic of chemical methodology might ultimately be applied to increasingly complex molecular constructs in biology. This could allow principles developed at the simple, small-molecule level to progress hierarchically even to manipulation of physiology.
Topics & Concepts
OrganismSelectivityChemistryBiological organismFunction (biology)Chemical biologyLiving systemsModel organismLiving cellMechanism (biology)BiomoleculeComputational biologyBiochemical engineeringCombinatorial chemistryBiological systemComputer scienceGeneBiologyBiochemistryGeneticsBiological materialsArtificial intelligenceEpistemologyEngineeringCatalysisPhilosophyBiotin and Related StudiesClick Chemistry and ApplicationsRNA and protein synthesis mechanisms