Antimicrobial peptides and other peptide-like therapeutics as promising candidates to combat SARS-CoV-2
Masoumeh Sadat Mousavi Maleki, Mosayeb Rostamian, Hamid Madanchi
Abstract
: Regarding the lack and the limitations of drugs against COVID-19, AMPs, AVPs, and other peptide-like compounds such as peptidomimetics have captured the attention of researchers due to their potential antiviral activities. Some of these compounds comprise unique properties and have demonstrated the potential to fight SARS-CoV2, particularly melittin, lactoferrin, enfuvirtide, and rupintrivir that have the potential to enter animal and clinical trials for the treatment of COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Antimicrobial peptidesAntimicrobial2019-20 coronavirus outbreakPeptideCoronavirusMedicineComputational biologyVirologyDiseaseBiologyInfectious disease (medical specialty)MicrobiologyBiochemistryInternal medicineOutbreakAntimicrobial Peptides and ActivitiesSARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches