Detection of new phytochemical compounds from <i>Vassobia breviflora</i> (Sendtn.) Hunz: antioxidant, cytotoxic, and antibacterial activity of the hexane extract
Altevir Rossato Viana, Bruna Godoy Noro, Daniel Santos, Katianne Wolf, Yasmin Sudatti das Neves, Rafael Noal Moresco, Aline Ferreira Ourique, Érico M.M. Flores, Cristiano Rodrigo Bohn Rhoden, Luciana Maria Fontanari Krause, Bruno Stefanello Vizzotto
Abstract
extract exhibited inhibitory, bactericidal, and antibiofilm action in biofilm-forming bacteria. The hexane extract exhibited cytotoxicity against melanoma, lung cancer, glioblastoma, leukemia, uterine colon, and hepatocarcinoma tumor cells. In addition, all tested strains resulted in increased production of ROS. This plant extract may be considered in future as an alternative for development of new therapeutic options aimed at the treatment of diverse pathologies.
Topics & Concepts
PhytochemicalChemistryDPPHAntioxidantABTSAntimicrobialCytotoxicityHexaneTraditional medicineFood scienceBiochemistryChromatographyOrganic chemistryIn vitroMedicineEssential Oils and Antimicrobial ActivityPhytochemicals and Medicinal PlantsPhytochemistry Medicinal Plant Applications