Litcius/Paper detail

BRG1 mediates protective ability of spermidine to ameliorate osteoarthritic cartilage by Nrf2/KEAP1 and STAT3 signaling pathway

Xinjie Mao, Bing Yan, Hongjie Chen, Lai Peng, Jinzhong Ma

2023International Immunopharmacology13 citationsDOI

Topics & Concepts

KEAP1SpermidineCartilageChemistryIn vivoInflammationSmall interfering RNAOsteoarthritisOxidative stressIn vitroDownregulation and upregulationLipopolysaccharideAggrecanPharmacologyCell biologyMolecular biologyCancer researchImmunologyBiochemistryTransfectionMedicinePathologyBiologyTranscription factorAnatomyEnzymeGeneBiotechnologyAlternative medicineArticular cartilageOsteoarthritis Treatment and MechanismsDendrimers and Hyperbranched PolymersStudies on Chitinases and Chitosanases